The SOUL trial (2025), a large-scale, double-blind, placebo-controlled study, evaluated once-daily oral semaglutide in 9,650 patients with T2DM and established atherosclerotic cardiovascular disease, chronic kidney disease, or both
Some clients feel a difference right away
Early studies look good right now
Because electronic health records are classified as sensitive data by the UK Data Protection Act, information governance restrictions (to protect patient confidentiality) prevent data sharing via public deposition
Some foods that increase GLP-1 due to their healthy fats include: avocados nuts olive oil fatty fish, like salmon Dark chocolate is rich in flavonoids that may support GLP-1 activity
Nature 320 , 362365 (1986)