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144,145,146,147,148,149,150,151,152 Once in the intestinal lumen, UA can either be directly excreted or metabolized by the gut microbiota

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Marinho HS, Real C, Cyrne L, Soares H, Antunes F

Glutamate acts through eight ionotropic and metabotropic receptor subtypes (mGluR1mGluR8) that have been classified into three groups: Group I receptors (mGluR1 and mGluR5) are coupled to G q proteins and phospholipase C and are involved in central sensitization and pain chronification

Accessed March 4, 2026