10.1016/0005-2760(90)90118-H 61 WuK
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Generally speaking, such mechanisms are tightly coupled to metabolic effects: from modulating redox balance and ferroptosis sensitivity to reshaping immune metabolism in the tumor microenvironment
Staskin D et al (2024): Efficacy and Safety of Vibegron for Persistent Symptoms of Overactive Bladder in Men Being Pharmacologically Treated for Benign Prostatic Hyperplasia: Results From the Phase 3 Randomized Controlled COURAGE Trial
doi: 10.1007/s00394-020-02188-2 42
Surprisingly, our results suggest that GPX4 has dual functions in Raji cells: it inhibits cellular activity on the one hand and promotes EBV replication and proliferation on the other hand when GPX4 expression is inhibited