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Roll the vial gently rather than shaking to mix the solution without damaging fragile peptide bonds

Researchers comparing semaglutide vs tirzepatide or retatrutide vs semaglutide should consider that formulation differences can affect outcomes, tolerability, and cost

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Clinical trials of semaglutide in the SUSTAIN and STEP programs demonstrated average weight loss of 15% to 22% of baseline body weight over 68 weeks, with many participants achieving these results as monotherapy

*Correspondence: Cheng Zhang, [email protected]