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Among the drug-induced DNA lesions, abasic (apurinic/apyrimidinic, AP) sites are one of the most common types in cells, and can lead to more deleterious lesions such as DNA strand breaks [4, 5]

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50 ml of venous blood was drawn and collected from subjects during the Pre-screening, Visit #1, and Visit #3, but not during the Visit #2 (midway-point)

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