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The primary molecular mechanism of TB-500 involves regulation of actin dynamics through its high-affinity binding to monomeric G-actin

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Primary Research Areas Tendon, ligament and muscle injury repair: documented across transection, crush and detachment models with measurable improvements in load-to-failure, collagen organization and functional recovery scoring [1,2]

In the lungs, mucus is constantly secreted by epithelial, goblet cells, and submucosal glands to maintain clear and clean airways (Ermund et al., 2017

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Pretreatment with candesartan (1 mg/kg/d, for 3 d before the LPS treatment) lessens LPS-induced ACTH and corticosterone release and reduces gene expression of cyclooxygenase-2 (COX-2), IL-6, and TNF- (105)