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51825189, Dec

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Chen, Y.C., Yang, Y., Zhang, C., Chen, H.Y., Chen, F., and Wang, K.J., Front

Unlike human growth hormone, which can induce hyperglycemia and reduce insulin secretion during extended use, AOD-9604 showed no adverse effect on insulin sensitivity even in long-term animal studies confirmed through euglycemic clamp techniques

Isolated MM cells were cultured in Iscoves modified Dulbecos medium supplemented with 20% FBS, insulin, selenium, transferrin, 10 g/ml of gentamycin, 10 ng/ml of interleukin-6, insulin-like growth factor-1 and vascular endothelial growth factor