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To address the challenges mentioned and promote the clinical translation of ROS-targeted agents, we could improve drug absorption and distribution by optimizing the chemical structure of the drug or using delivery systems like nanoparticles

It is generally agreed that we have no evidence that febuxostat is a negative for the heart, just the question of the CARES trial as to whether it is not as protective as allopurinol

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Acknowledgements The authors thank Dr

It works through two receptors: GLP-1 suppresses appetite and slows digestion, and GIP supports insulin sensitivity and metabolic efficiency