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Research has also described a distinct potency pattern across its receptor targets: This balanced profile provides a framework for studying coordinated metabolic responses rather than isolated single-pathway effects

PLoS ONE 9 , e112498 (2014)

Area postrema GLP-1 receptor signaling mediates nausea-like behavior in rodents

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Prominin 2 has a typical membrane topology with five transmembrane segments and two large glycosylated extracellular loops [74]