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LRP5 is vital to the Wnt/beta-catenin signaling pathway, which is involved in a variety of biological processes

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EDS affects connective tissues, which results in symptoms that range from mild joint effects to life-threatening complications

However, some patients report leg discomfort potentially related to rapid weight loss, electrolyte imbalances from gastrointestinal side effects, or increased physical activity rather than direct drug effects

Van Bloemendaal L, IJzerman RG, Ten Kulve JS, Barkhof F, Konrad RJ, Drent ML, et al

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