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According to FDA prescribing information, gastrointestinal adverse events led to treatment discontinuation in approximately 4-7% of patients in clinical trials, with rates varying by dose and indication

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Convulsions have been reported with this concurrent use

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Then, the membranes were further incubated with secondary antibodies (goat-anti rabbit or anti mouse antibodies, Beyotime, Shanghai, China) for 2 h at room temperature

Finally, though glucose use for fatty acid synthesis is strongly suppressed in the absence of ACLY, it is not fully blocked in vitro or in vivo 4,6