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However, CagriBB has equivalent potency to Cagri, in CRE-reporter assays in mammalian cells expressing AMY 3 Rs (Supplementary Table 4), suggesting there is negligible impact of this rotamer difference

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Research has examined its potential involvement in musculoskeletal, gastrointestinal, and vascular research frameworks

Conversely, AAVs have a limited packaging size of ~5 kb with significantly milder inflammatory risk [143]

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If symptoms significantly impact daily functioning beyond the first week at a new dose, consider extending that dose level for an additional four weeks before increasing