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[23] NICE guidance emphasises that GLP-1 medications should be combined with lifestyle modifications, including dietary changes and increased physical activity, to optimise outcomes
Many of these laxatives have been in use for hundreds of years
Berberine-Induced Glucagon-Like Peptide-1 and its Mechanism for Controlling Type 2 Diabetes
Conversely, NO acts as an inhibitory neurotransmitter related to LES relaxation
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However, it does not significantly increase the risk of severe infection unless the individual has diabetes (Nauseef 1988)
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