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Figure 1 The L-cells derived cocktail of hormones is believed to play pivotal roles in digestion, for example slowing down the GI motility (PYY) and suppressing the appetite in vivo (GLP-1, oxyntomodulin, PYY), apparently in response to direct sensing of the gut luminal content via G-protein coupled receptors or through neuronal circuits (43, 52)

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doi: 10.1016/j.annonc.2020.02.016 12

It may also create other problems, especially for patients who use GLP-1 medication for diabetes management, appetite, or significant weight-related health concerns

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[9] He appeared in the bodybuilding documentary Pumping Iron (1977), which set him on his way to a career in films