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Exploratory pilot study of exogenous sustained-release melatonin on nocturia in Parkinsons disease

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5 Briefly, the conversion of dietary precursors into TMA involves four enzymatic pathways, including the choline-utilizing TMA lyase system (CutC/D), the carnitine Rieske-type oxygenase/reductase system (CntA/B), betaine reductase, and TMAO reductase

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10.1124/jpet.109.153973

Cellular and Molecular Neurobiology , 44(1), 1-16