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MTHFR and Vitamin B12 Absorption The MTHFR genetic mutation has a negative effect on B12 absorption, with studies showing an increased prevalence of low blood levels of vitamin B12 in those with the mutation

The treatment also decreased pro-inflammatory and pro-fibrotic gene expression with reduced macrophage infiltration (Li et al., 2025)

A Noble Metal Substitution Leads to B12 Antimetabolites

However, absorption challenges and individual variability in effectiveness have led many Richmond healthcare providers to recommend vitamin B12 injections as a more reliable delivery method

Our Vitamin B12 injections are an excellent option for those looking to improve their vitality and mental clarity

Preferred Injection Sites and Techniques The deltoid and gluteal muscles are often used for B12 injections