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"We thought we would find that it signaled to the hypothalamus (which is widely implicated in body weight regulation), so we were very surprised to discover that the signal was to the hindbrain, which is where the GLP-1 analogs are believed to act." CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER The brain circuit behind these metabolic benefits appears to work by "mediating the effects of FGF21," Potthoff said a process that can also be linked to side effects like gastrointestinal issues and, in some cases, bone loss

According to a 2019 clinical review report by the Canadian Agency for Drugs and Technologies in Health, Ozempic may help to improve glycemic control ( 4 )