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Sun-exposed areas are most common, but skin cancer can form on any part of the leg

*Pooyandjoo 2016 study: effects observed in a 4 to 8-week course, variable depending on individuals and context (caloric deficit, physical activity)

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Remarkably, 5-cholesten-3-one, derived by oxidation of the 3-hydroxyl group of cholesterol, is not a substrate in spite of a structure of the A and B rings identical to that in 5-AD and 5-PD, in which the double bond isomerization occurs (Figure 2)

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