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Experimental challenges also remain, including limited tools for real-time monitoring of GLR-mediated NO flux and the absence of plant mutants that mimic neurodegenerative phenotypes

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Hadzhieva M, Kirches E, Wilisch-Neumann A, Pachow D, Wallesch M, Schoenfeld P et al (2013) Dysregulation of iron protein expression in the G93A model of amyotrophic lateral sclerosis

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473 Mixed lineage kinase 3, a member of the MAP3K family, regulates the JNK/p53 pathway to mediate SLC7A11 expression and oxidative stress, causing myocardial fibrosis in the late stage of chronic heart failure in the TAC mouse model