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Patients with prior GERD, reflux-like symptoms, or related conditions were excluded to reduce bias, according to study results published in Annals of Internal Medicine

P., Tate, C

Adults with Overweight & Comorbidities: Individuals with a BMI of 27 kg/m or higher who also have at least one weight-related medical condition, such as hypertension (high blood pressure), type 2 diabetes, or dyslipidemia (high cholesterol)

Helicobacter (Osaki et al., 2008

Lixisenatide: Gastrointestinal: acute pancreatitis, hemorrhagic and necrotizing pancreatitis, ileus, intestinal obstruction, severe constipation including fecal impaction Hepatobiliary: cholecystitis, cholelithiasis requiring cholecystectomy Neurologic: dysgeusia, dysesthesia Pulmonary: pulmonary aspiration has occurred in patients receiving GLP-1 receptor agonists under-going elective surgeries or procedures requiring general anesthesia or deep sedation