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Proc Natl Acad Sci USA 1992

Hyaluronic Acid pulls in and holds on to moisture

4.4 Interactions between cartilage and synovium 4.4.1 Interplay between cytokines released by chondrocytes and synovial cells When cartilage is damaged, chondrocytes release proteoglycan fragments, type II collagen fragments, and diverse injury-associated factors that synovial cell surface pattern recognition receptors (PRRs) can detect, prompting synovial hyperplasia and proinflammatory cytokine secretion (139)

Rinse thoroughly and pat dry

For an excellent primer on what this process looks like, listen to Episode 127 of Resiliency Radio with Jim Tomlinson

Sulforaphane treatment also led to suppression of key colorectal cancer stem cell markers, such as CD44 and CD133 in HCT116 and SW480 spheroids, facilitated by the TAp63 /Lgr5/ -catenin pathway (Wang et al., 2021)