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Robert Kushner: Well, GLP-1 and its sister drug GIP were first identified actually in the 1980s

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Dosing schedule (per Health Canada ): Starter dose: 0.25 mg once weekly for the first 4 weeks Increase: 0.5 mg after Week 4, if tolerated Further titration: Up to 1 mg or more, depending on your treatment plan The gradual increases, occurring every 4 weeks, are designed to minimize side effects and promote a safer, more sustainable treatment response