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In the study by in vitro on anaplastic thyroid cells, it was demonstrated that the treatment with rosiglitazone reduced anchorage-dependent and -independent growth and migration of TC cells, and increased apoptosis rate by reducing Bcl-X(L) expression and caspase-3 and -7 activation

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Bariatric surgery is also capable of producing weight loss and reducing diabetes severity, especially in severe obesity

In addition, GIP enhances the lipid buffering capacity of WAT in lipid metabolism and promotes suitable lipid allocation, thereby reducing ectopic fat deposition [134]