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This requirement is in place because bacteriostatic water is used to dilute or reconstitute injectable medications, and improper use without medical supervision can pose significant health risks

Mnatsakanyan, H., Serra, R

10.1113/jphysiol.1973.sp010273 J

Desensitization protocols typically take weeks or even months, depending on the patients response and the severity of their condition

While the latter might be relevant to conditions such as pathogen challenge, current concepts suggest that the relatively low antioxidant complement of the apoplast enables this compartment to exist in a more oxidized state compared to the cell interior (Pignocchi et al

Significantly, no overt toxicity was noted during 96 day studies