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Absorption Routes: Liberated B12 can be absorbed via two distinct routes: (1) binding to the intrinsic factor (IF) protein or (2) being taken into the gastrointestinal mucosa by diffusion

However, understanding the subtle differences helps patients and families make informed decisions about treatment options

In some cases, it can affect reproductive health negatively

For instance, in one 1960s study of intravenous NAD+ for addiction, patients who received a fast IV drip experienced immediate headache and shortness of breath, whereas those given the same dose at a slower drip rate (under ~35 drops/min) had no distress

In severe cases, doctors may recommend hydroxocobalamin injections for the rest of the persons life

Vitamin B12 injections are available through your GP if medically required