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We stated that we welcome additional information that compares outcome data from the Axoguard HA+ Nerve Protector TM and the predicate device, the Axoguard Nerve Protector TM , to help inform our assessment of whether the Axoguard HA+ Nerve Protector TM demonstrates a substantial clinical improvement

However, and interestingly, data also suggested that while GSTP1-1 engages TRAF2 in its dimeric form, only one monomer is involved in binding and therefore the other may still be catalitically competent 30

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Most respondents (66%) considered current evidence insufficient to guide practice and 95% supported a clinical trial