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Finding an inability of brand name GLP-1 manufacturers to keep up with patient demand for approved GLP-1 drugs, the FDA temporarily placed many of the approved GLP-1 drugs on the FDA shortage list, leading to an increase in the availability and sale of compounded drugs containing the active ingredient

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Because it was considered unethical to continue administering a placebo, the trial was terminated early

Patients using expired doses may experience weaker appetite suppression, inconsistent blood glucose control, or delayed weight-management benefitsoutcomes often misattributed to individual non-response rather than medication potency loss