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PMCID: PMC10546481

[3] [4] The prescribing clinician should be fully informed about your levothyroxine use, dosage, and thyroid condition history

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The discovery of this gut-brain interaction provides potential targets for antidepressant therapy, potentially optimizing treatment outcomes by regulating specific gut microbiota and sphingolipid metabolic pathways

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The next challenge for researchers devoted to the connection between inflammation, glutamate, and depression will be to reduce depression-causing inflammation without dampening the power of the immune system to fight disease