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Key Takeaways Epithalon is a synthetic tetrapeptide that supports longevity, deep sleep, and cellular renewal through a mechanism linked to the pineal gland and telomere biology

There is also an increased sensitization of the excitatory neurotransmitter system, such as NMDA glutamate receptors, the reduction in the number of GABA receptors (downregulation), the shift of benzodiazepine receptors to an inverse agonist state, and compensatory changes in other components of the macromolecular GABA/benzodiazepine/chloride ionophore complex (for review see, i.e., [219,220,221,222,223,224,225])

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In some cases, ultrasound imaging is used to help guide the needle to the correct site

The lack of clinical trials means there is little reliable data on its safety, efficacy, or long-term effects

BPC 157 Cream is formulated into an external dosage form of this polypeptide