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Environ Toxicol Chem 40:71577166 Mutlib AE (2008) Application of stable isotope-labeled compounds in metabolism and in metabolism-mediated toxicity studies

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Optimization of treatment trains within this design space increasingly relies on digital and data-driven approaches

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With this early rescue dose, the patient likely survives because the dashed black curve in Panel B stays well above the 30% level for functional hepatocytes, which is thought to indicate liver failure

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