rate of weight loss on tirzepatide Study: produces greater vs. other GLP-1s Tirzepatide Dosing for Weight Loss

Kido J, Inoue H, Shimotsu H et al (2020) Effect of L-carnitine on amino acid metabolism in elderly patients undergoing regular hemodialysis

Side Effects: See Figure 2

Hormonal therapies included Arimidex (anastrozole), tamoxifen, Aromasin (exemestane), and Femara (letrozole)

2023;72:128-OR

For more than two decades, researchers pursued the goal of delivering GLP-1 receptor activation through an oral tablet, a pursuit complicated by the fundamental biochemistry of peptide drugs: their vulnerability to acid hydrolysis in the stomach, enzymatic degradation in the gastrointestinal tract, and poor absorption across the intestinal epithelium

they also decrease appetite, which often results in weight loss, and several of these drugs reduce the risk of heart disease (heart attacks and strokes)