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In human hippocampal progenitor cells, the IL-1-induced increases in KP enzymatic activity and the subsequent dampening of neurogenesis was reversed with co-treatment with a KMO inhibitor, which would reduce the levels of 3-HK and QA [116]

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Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer

reported a significant decrease in PD-L1 transcription after inhibiting PGE2 anabolism by COX2 inhibitors or enhancing PGE2 catabolism