Stable at room temperature
These in vitro results demonstrated that H2O2 induces Leydig cell senescence, accompanied by FOXO4 nuclear translocation and activation of senescence pathways
These factors dont directly cause SIBO, but they make it more likely to develop or return when combined with motility or structural issues
When it comes to the gut, apigenin affects Enterococcus caccae cell wall/membrane synthesis and increases the incidence of protein misfolding Bacteroides galacturonicus growth was also inhibited by apigenin[and] apigenin promoted overall growth and diversity, lowered Firmicutes to Bacteroidetes ratio, and promoted production of short chain fatty acids, including butyrate, which is associated with health (Wang et al., 2017)
It's tough
Sanders MC, Goldstein AL, Wang YL