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For many peptides promoted for anti-ageing and skin health, high-quality human evidence remains limited

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The following relevant parameters were determined where possible: area under the concentration-time curve from time zero to the last time point (AUCo-iast) or extrapolated to infinity (AUCo- ), C ma x concentration in plasma extrapolated to time zero (Co), terminal elimination half-life (tj 2), volume of distribution (Vd), and clearance (CL)

Our approach

doi: 10.3389/fpsyt.2021.669089 Received 17 February 2021 Accepted 16 August 2021 Published 30 September 2021 Volume 12 - 2021 Edited by Francesca Bonomini, University of Brescia, Italy Reviewed by Mostafa Waly, Sultan Qaboos University, Oman

Vill K, Muller-Felber W, Landfarth T, Koppl C, Herzig N, Knerr C, Holla H, Steidle G, Harms E, Hohenfellner K, Interdisciplinary Cystinosis Group (2022) Neuromuscular conditions and the impact of cystine-depleting therapy in infantile nephropathic cystinosis: a cross-sectional analysis of 55 patients