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Noncardiac comorbidities in heart failure with preserved ejection fraction commonly ignored fact

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We administered saline plus vehicle (control) and RSL3 or 5-FU alone and in combination (i.e., 5-FU plus RSL3)

All animal experiments followed protocols approved by The Scripps Research Institute IACUC (protocol 09-0111), Johannes Gutenberg University Medical Centre Mainz (Landesuntersuchungsamt Koblenz, AZ 23-177-07/G14-1-55 and G 19-1-063), or the Institutional Animal Research Committee of Tongji Medical College (IACUC no