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PTX-3 was found to be an independent inflammatory marker correlated with the presence of LV diastolic dysfunction and HFpEF ( Table 1 ).49 In the CANTOS trial, when canakinumab succeeded in lowering high-sensitivity CRP below 2 mg/l, the likelihood of HF hospitalisation was lower.50 This study did not discriminate between HFrEF and HFpEF, yet patients were old and had a high prevalence of obesity, diabetes and arterial hypertension

Its 180,000+ studies over decades

doi: 10.1016/0014-4835(82)90039-2

Thus, we can exclude a direct uncatalyzed reduction of roGFP2 WT (S 2 ) by GSH (i.e

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