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Ascorbate can also scavenge nonradical reactive species, derived from peroxynitrite, such as hypochlorous acid, ozone, and nitrating agents

We also looked at overlapping CPAP prescriptions and signals for CPAP discontinuation, which was proxied by a six-month gap in CPAP-related claims referred to as CPAP engagement (while this does not confirm clinical discontinuation, differences before and after approval provide meaningful directional insights)

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Gudkov, p16(Ink4a) and senescence-associated -galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli