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GLP-1s have been shown to reduce inflammatory markers, which can help calm the inflammatory environment that contributes to pain and disease activity

Gut microbiota carry out several additional bile acid metabolic reactions that includes dehydroxylation of the hydroxy groups on the steroid backbone

(often used together in equimolar or matched doses, 12 times daily, depending on study objectives)[1][4]

Yamada et al., 2020)

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