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This is all very hand-wavy theory right now, but could it be the insulin thats having some of these effects in the brain? It is clear that insulin dysregulation affects the brain, as evidenced by certain neurodegenerative diseases

That, in and of itself, improves a lot of things

Additionally, loss of muscle mass during rapid weight loss can reduce the efficiency of muscle pumps that help return blood from the extremities to the heart, leading to blood stasis, particularly in the legs, which is a risk factor for deep vein thrombosis (DVT)

Semaglutide is best suited for people with significant weight to lose, typically those with a BMI of 30 or higher, or 27 or higher with weight-related health conditions

A branded form of oral semaglutide tablets sells under the brand name Rybelsus and provides a 3mg daily tablet

Hold the needle at a 90-degree angle to your skin, and insert it between your 2 fingers