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Therapeutic Dose: The final target dose for weight loss is typically 25 mg or 50 mg daily

Its phase 3 drug survodutide is a GLP-1 receptor dual agonist that works by activating the glucagon and GLP-1 receptors simultaneously that are meant to reduce body weight by both boosting energy burn and reducing food intake

Real-world evidence from observational studies consistently shows that GLP-1 RA use is associated with reduced risk of hepatic decompensation even in patients with established cirrhosis, supporting cautious use in this population

287 , R1190R1193 (2004)

data collection, analysis, and interpretation of the data

The DPP-4 enzyme breaks down GLP-1 within 2-3 minutes of secretion