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Improved Sleep Apnea: Weight loss can reduce the severity of Obstructive Sleep Apnea, often leading to better sleep quality

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Further, 43.7% of orforglipron recipients in cohort 1 maintained at least 80% of the weight loss achieved in SURMOUNT-5, compared to 16.4% of placebo recipients

It definitely helped to give me the kick start I needed for weight loss but I can do it without so I'm glad I stopped it when I did

It can make it hard to move the limbs and can cause muscle spasms or cramps

Risk of depression with GLP-1 receptor agonists use in overweight or obese adults with type 2 diabetes: A new-user, active-comparator cohort study