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Description

( A ) The in vitro PARylation assay was performed using purified GST or GST-RSMC and Flag-PARP1 in the absence or presence of olaparib (20 M) in the reaction buffer at 37 C for 1 h

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PMID: 39353532 L-Glutathione reduced purchased from MedChemExpress

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Hyperpigmentation was observed when this compound got oxidized and inactivated by factors such as heat, radiation and inflammation with consequent loss of the inhibitory effect on tyrosinase

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However, if the "clean-up crew" (antioxidants) is understaffed, that inflammatory response can stay "on" for too long

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Genome Biology

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Health 14 , 1557988320959993 (2020)

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