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**Extended breaks (2+ weeks) require provider guidance for resumption** 5

A patient with a lower BMI but significant metabolic risk may need a different strategy than a patient with a higher BMI, severe cravings, insulin resistance, and prior medication intolerance

J Toxicol Environ Health A 69 : 12611284 Brown LA, Ping XD, Harris FL, Gauthier TW 2007 Glutathione availability modulates alveolar macrophage function in the chronic ethanol-fed rat