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These drugs mimic the action of glucagon-like peptide-1 (GLP-1), a naturally occurring hormone in the body that plays a key role in regulating blood sugar levels, satiety, and digestion

Unraveling the safety profile of glp-1 receptor agonists: Mechanistic insights with a focus on semaglutide

J Biol Chem 285: 1438914398, 2010

Central versus systemic comparison All mice were ICV-cannulated

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( A ) Mouse caSMCs were transfected with a combination of 4 MTP-specific siRNAs, and relative Mtpa mRNA expression was measured by reverse transcription PCR versus control siRNA