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Any changes are usually gradual over weeks rather than immediate

Similar to dexpramipexole, absence of rigorous evaluation in preclinical studies may have led to its failure

Claims submitted outside the stated timeframe will not be eligible for review

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It should be taken as follows: Once daily, every morning On an empty stomach before eating, drinking or taking any other medication Swallowed whole with up to 120ml of water more than this reduces absorption Wait at least 30 minutes before eating, drinking or taking other medicines Patients start on the lowest dose and increase it gradually every 30 days