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Loss of GPx2 increases apoptosis, mitosis, and GPx1 expression in the intestine of mice

Five positions judged to govern ketosteroid isomerase activity based on mutational studies ( The catalytic efficiency of HsaGST A3-3 with 5-AD is 5000-fold higher than that of HsaGST A2-2, and we found that mutating the five residues in the H-site of HsaGST A2-2 into the corresponding HsaGST A3-3 residues enhanced the efficiency to 70% of the HsaGST A3-3 value (Table 1)

Article Details Issue Section The journal allows the authors to hold the copyright without restrictions and allow the authors to retain publishing rights without restrictions

Primary Fuel for the GI Tract The cells of the small intestine have a high turnover rate and require immense energy to function

References 1 Abdel-HamidN.FaddahL.Al-RehanyM.AliA.BakeetA

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