This finding agrees with the literature whereby the role of quinone redox metabolism is an ambiguous source of toxicity, with evidence suggesting that redox cycling requires supra-pharmacological concentrations of doxorubicin to generate substantial ROS in tissues and cells 10
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Roles of GSK-3 and -catenin in antiviral innate immune sensing of nucleic acids
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Finally, eryptotic RBCs are engulfed and processed by Kupffer cells, the phagosome containing eryptotic RBCs merges with lysosomal vesicles, obtaining a complex called the erythrophagolysosome
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