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This article is based on previously conducted studies and does not contain any studies with human participants or animals performed by any of the authors

During the first week on semaglutide or any dose increase, you might not know how you will respond

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Orally administered semaglutide was administered for 10 consecutive days with dose escalation on the 5th day (5 days of 5 mg dosing followed by five days of 10 mg dosing) to avoid gastrointestinal side effects in both normal and renally impaired subjects