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Phase 2 trial of talampanel, a glutamate receptor inhibitor, for adults with recurrent malignant gliomas

For example, luteolin (a flavonoid from Chrysanthemum and others) decreased infarct size and improved cardiac function in rat I/R models via Nrf2 activation and HO-1 upregulation (Oyagbemi et al., 2018)

(Many plant oils tend to go off pretty quickly)

Others, like KPV and GHK-Cu, dont have adequate safety data in humans

The primary endpoints included nitric oxide production, extracellular reactive oxygen species bioactivity, endothelial function, and mitochondrial oxidative stress, with further investigation into the mechanistic role of the oxLDLLOX1 signaling pathway

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