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UK SmPCs note that in rodent studies, some GLP-1 agonists caused thyroid C-cell tumours, though the clinical relevance in humans is unknown

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Thus, it is possible that these data support the idea that peripheral and central GLP1 may act independently as well as additively to suppress food intake (Brierley et al., 2020)

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[6] These properties underlie the interest in MB as a neuroprotective or nootropic agent, by bolstering mitochondrial activity in neurons, MB might support cognitive processes such as memory and learning, although clinical evidence is still emerging